Hereditary Hemochromatosis: A Shockingly Common Genetic Disease

Tuesday, February 26th, 2008

What is hereditary hemochromatosis?

Hereditary hemochromatosis, referred to as HH, is a common iron overload genetic disorder. A person with hereditary hemochromatosis absorbs and stores excess amounts of iron in the body. This extra iron settles in the liver, skin, and pancreas and, if left untreated, gradually develops iron deposits that cause organ and tissue deterioration.

What causes hereditary hemochromatosis?

The HFE gene in humans monitors iron absorption; a mutated HFE gene allows too much iron absorbtion and causes hereditary hemochromatosis. People with the hereditary hemochromatosis gene are carriers for the disease. If two carriers have a child, that child will develop hereditary hemochromatosis. Recently, researchers from both the European Molecular Biology Laboratory and the University of Heidelberg, Germany, discovered that HH is a liver disease. Research lab mice that were genetically engineered to lack HFE only in liver cells showed all the key features of hereditary hemochromatosis.

How common is hereditary hemochromatosis?

Hereditary hemochromatosis is one of the most common genetic diseases in the U.S.; almost 1 in 10 American Caucasians carries the gene. Caucasians with ancestry in Northern Europe are most commonly the carriers of the HH gene. Hereditary hemochromatosis is uncommon but still occurs among African Americans, Asian Americans, and Latinos.

What’s the danger of hereditary hemochromatosis?

If left untreated, iron accumulations due to hereditary hemochromatosis could potentially lead to other serious health issues, such as arthritis, liver failure, congestive heart failure, impotence, skin pigmentation, and pancreas damage. Without previous testing for hereditary hemochromatosis, most people are unaware that they have the disease. Most symptoms don’t appear until after about age 30 for men and 50 for women.

Screening for hereditary hemochromatosis is easy.

There is good news, though–testing for hereditary hemochromatosis is painless and simple. A fairly inexpensive, quick cheeck swab test kit you can use at home that will show if you have the mutated HFE gene that results in hereditary hemochromatosis is available from HealthCheckUSA. You shouldn’t take iron supplements until you know your test’s results. If your test’s results do show that you have hereditary hemochromatosis, treatment comes in the form of routine blood removal, usually several times a year.

Cancer screenings

Monday, December 17th, 2007

Cancer screenings: fear is the killer

Cancer screenings are one of the most important kinds of laboratory tests you can take. What’s so important about cancer screenings, you ask?

A personal cancer screening story

A favorite uncle and aunt of mine used to live overseas with my cousin James. James and his parents were a treat, if one rarely seen. They never complained, and always had a ready smile or joke. Honest people for whom every moment was a simple pleasure.

And so it was, because Aunt Mary had cancer. She never got a cancer screening; she just lived with the pain, perhaps afraid of what a cancer screening would tell her, perhaps already believing that the cancer would kill her before age 50 and devastate the family. Rather than tell her husband and get a cancer screening, she kept the disease hidden, preferring to avoid cancer treatments and enjoy the time she had.

Cancer screenings shed light

Our grief at her passing was accentuated knowing that she could’ve lived a full life with a timely cancer screening like one of the three cancer screenings offered by HealthCheckUSA. An early cancer screening would’ve allowed her to get a doctor’s diagnosis, avoid long chemotherapy and strike at the cancer pre-emptively. HealthCheckUSA really can be your best defense against disease.

The HealthCheckUSA cancer screening difference

Cancer screenings at HealthCheckUSA provide you with important advantages. They generally cost much less than the lab tests you’d order at a hospital because there are no hidden markups. A fully accredited medical reference laboratory analyzes every cancer screening result. These are the same cancer screenings ordered by physicians. However, with HealthCheckUSA cancer screenings, you control what tests you take and when.

Nothing beats the peace of mind of a HealthCheckUSA cancer screening. If you suspect you might be at risk for ovarian cancer, colon cancer or prostate cancer, order a health test at our website today.

AIDS testing: if only it was that simple for everyone

Wednesday, August 22nd, 2007

AIDS testing is a cut-and-dried reality for most of us lucky enough to be reading blogs on the Internet. We know what AIDS testing is, and we know when to get tested for AIDS. We know what it does, and we have a pretty good concept of the dangers and symptoms of AIDS.

We’re really, really fortunate.

Babalwa Tembani is a 21-year-old woman who lives in Cape Town, South Africa. At the age of 14, she was raped by her HIV-positive uncle because he believed the myth that sex with a virgin would cure him of the virus. Now Babalwa is infected and must take anti-AIDS drugs regularly to stay alive.

If her uncle had known a little more about AIDS, Babalwa would probably be looking at a bright future, full of promise. Instead, her health will always be a black cloud hovering over her ominously.

A little knowledge goes a long way. HealthCheckUSA provides quality AIDS testing at affordable prices, but if a person doesn’t know that they need to be tested, they’ll never find out about their health, and they may end up curtailing their lives and those of the people they love. And that’s not the only ignorance that might prevent them from pursuing AIDS testing.

If a person believes some of the many myths about AIDS, they may fail to seek out the medical help that can save their lives. These myths are widespread; they’re not South African. For example:

  • AIDS is nearly always fatal so testing is futile (in reality, quick diagnosis can save lives),
  • AIDS can always be cured by modern medications, so there’s no reason to worry or rush to be tested (it can’t - success rates are about 80%),
  • AIDS was developed by the government to kill minorities (a survey of Texan Latinos and blacks found that some 30% of that population believes this),
  • AIDS doesn’t exist, and is a conspiracy to marginalize the gay community (untrue).

I’d be the last person to trumpet the glories of public education in the Western world. The First World can alarmingly rank last at things. (In fact, South Africa is considered a first-world country by many.) But I am grateful to the teachers, public health officials and medical professionals - and yes, even the news media - who have successfully educated me and my loved ones about AIDS testing. Although there’s still a daunting amount of myth-busting to be done, I’m privileged to have benefited from their guidance.

If only Babalwa Tembani were so lucky.